Developing Oncolytic Viruses for the Treatment of Cervical Cancer

نویسندگان

چکیده

Cervical cancer represents one of the most important malignancies among women worldwide. Current therapeutic approaches for cervical are reported not only to be inadequate metastatic cancer, but also considered as cytotoxic several patients leading serious side effects, which can have negative implications on quality life women. Therefore, there is an urgent need development innovative and effective treatment options. Oncolytic viruses eventually become biological agents, since they preferentially infect kill cells, while leaving normal tissue unaffected. Moreover, able leverage host immune system response limit tumor growth. This review aims systematically describe discuss different types oncolytic generated targeting well outcome combination virotherapy with conventional therapies. Although many preclinical studies evaluated efficacy in number clinical trials so far limited, their properties currently being tested other malignancies.

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ژورنال

عنوان ژورنال: Cells

سال: 2023

ISSN: ['2073-4409']

DOI: https://doi.org/10.3390/cells12141838